If you made it this far, thanks for visiting my personal page!
I am a recent PhD graduate from the Department of Biomedical Informatics at Columbia University Irving Medical Center, and a member of the Lappalainen Lab at the New York Genome Center. I currently live in New York City.
Check out my resume here
Education
Research
Broadly, I am excited by the modern integration of computer science, statistics, and biology in the interdisciplenary field of bioinformatics. Bioinformatics is sometimes classified as a subfield of “Biomedical Informatics,” which aims to interpret large data sets from all areas of healthcare, from population wide observation studies, to molecular interactions in disease systems. More on this here. Personally, I am most interested in the molecular basis of human phenotypes, which can now be studied through high throughput sequencing. In the Lappalainen lab, we study how genetic variation influences gene expression. This is an important question, both for basic biology and for studying the mechanisms of human genetic disease.
My scientific career started in college, when I worked in the Sela Lab studying microbial community ecology in food processing systems, primarily by analyzing 16S rRNA sequencing data.
Publications
Jonah E. Einson, Dafni A. Glinos, Pejman Mohammadi, Stephane E. Castel, Tuuli Lappalainen, 2022. “Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants.” https://www.biorxiv.org/content/10.1101/2023.01.31.526505v1
Jonah. E. Einson, Mariia Minaeva, Faiza Rafi, Tuuli Lappalainen, 2022. “The impact of genetically controlled splicing on exon inclusion and protein structure.” bioRxiv https://www.biorxiv.org/content/10.1101/2022.12.05.518915v1
Ferraro, Nicole M., Benjamin J. Strober, Jonah E. Einson, Nathan S. Abell, Francois Aguet, Alvaro N. Barbeira, Margot Brandt, et al. 2020. “Transcriptomic Signatures across Human Tissues Identify Functional Rare Genetic Variation.” Science 369 (6509). https://doi.org/10.1126/science.aaz5900.
Mohammadi, Pejman, Stephane E. Castel, Beryl B. Cummings, Jonah E. Einson, Christina Sousa, Paul Hoffman, Sandra Donkervoort, et al. 2019. “Genetic Regulatory Variation in Populations Informs Transcriptome Analysis in Rare Disease.” Science 366 (6463): 351–56. https://doi.org/10.1126/science.aay0256.
Cortes, Jose R., Ioan Filip, Robert Albero, Juan A. Patiño-Galindo, S. Aidan Quinn, Wen-Hsuan W. Lin, Anouchka P. Laurent, Bobby B. Shih, Jessie A. Brown, Anisha J. Cooke, Adam Mackey, Jonah Einson, Sakellarios Zairis, Alfredo Rivas-Delgado, Maria Antonella Laginestra, Stefano Pileri, Elias Campo,8 Govind Bhagat, Adolfo A. Ferrando, Raul Rabadan, and Teresa Palomero 2022. “Oncogenic Vav1-Myo1f Induces Therapeutically Targetable Macrophage-Rich Tumor Microenvironment in Peripheral T Cell Lymphoma.” Cell Reports 39 (3): 110695.https://doi.org/10.1016/j.celrep.2022.110695.
Jonah E. Einson, Asha Rani, Xiaomeng You, Allison A. Rodriguez, Clifton L. Randell, Tammy Barnaba, Mark K. Mammel, Michael L. Kotewicz, Christopher A. Elkins, and David A. Sela. 2018. “A Vegetable Fermentation Facility Hosts Distinct Microbiomes Reflecting the Production Environment.” Applied and Environmental Microbiology 84 (22). https://doi.org/10.1128/AEM.01680-18.
Sturgeon, Susan R., David A. Sela, Eva P. Browne, Jonah E. Einson, Asha Rani, Mohamed Halabi, Thomas Kania, et al. 2021. “Prediagnostic White Blood Cell DNA Methylation and Risk of Breast Cancer in the Prostate Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) Cohort.” Cancer Epidemiology and Prevention Biomarkers, January. https://doi.org/10.1158/1055-9965.EPI-20-1717.
You, Xiaomeng, Jonah E. Einson, Cynthia Lyliam Lopez-Pena, Mingyue Song, Hang Xiao, David Julian McClements, and David A. Sela. 2017. “Food-Grade Cationic Antimicrobial ε-Polylysine Transiently Alters the Gut Microbial Community and Predicted Metagenome Function in CD-1 Mice.” NPJ Science of Food 1 (December). https://doi.org/10.1038/s41538-017-0006-0.